Actually, the site wasn't designed with novices in mind, as evidenced by its tagline: "Technical Posters and Cheats for IT Guys." And it's easy to be thrown by some of the seriously techie subjects you'll find on the home page.
However, by browsing the Categories section on the righthand side, you'll find guides for plenty of mainstream stufff. Look in MS Office, for instance, for posters on Word, PowerPoint, and the like. Check Browsers for posters on Firefox and Internet Explorer. And so on.
Within each category you'll see a large preview of each poster, followed by a link for downloading a PDF you can then print.
What's great is that the site has guides for older versions of programs as well, like Publisher 97. (If you can't find something by perusing the Categories, try using the Search field.)
This is a great resource for anyone trying to learn a new piece of software, or for novice users who like paper cheat-sheets they can keep by their side. And I'm happy to note that all the TechPosters posters are free of charge.