Physical keys are so out. Pretty, light-emitting panes of curved glass are now where it's at.
The TransluSense uses cameras and infrared light to read the input and swipes from your hands. Instead of using a mouse, you use the keyboard's surface as a trackpad.
You can also place programmable, customizable skins over the top of the TransluSense so that it bears the layout you want: Turn it into the perfect PC gaming keyboard, for example, or one tailor-made for Excel.
Luminae is still working out some bugs, but, with luck, you'll be able to buy it in a year or two.